Project outputs and dissemination
Peer-reviewed publications
Interconnections between the food system and antimicrobial resistance: A systems-informed umbrella review from a One Health perspective
One Health, 2025
Human food systems are a major driver of antimicrobial resistance (AMR), with significant implications for human, animal, and ecosystem health. While recent research frames AMR as an emerging property of a complex system, this perspective has not been systematically applied to the existing evidence. This review aims to synthesise the evidence on AMR and the food system from a complex systems perspective, highlighting the interconnections between factors that contribute to AMR emergence and spread.
This review underscores the need for a One Health approach to AMR mitigation, given the interconnections between human, animal, and ecosystem health. Findings highlight the trade-offs in AMU and the economic incentives that may conflict with global antimicrobial stewardship. Further research may empirically explore connections to upstream factors, such as consumer preferences and environmental determinants.
Read the paper here.
Lead author: Chloe Clifford Astbury – Corresponding author: Tarra Penney
Integrated surveillance systems for antibiotic resistance in a One Health context: a scoping review
BMC Public Health, 2024
Antibiotic resistance (ABR) has emerged as a major threat to health. Properly informed decisions to mitigate this threat require surveillance systems that integrate information on resistant bacteria and antibiotic use in humans, animals, and the environment, in line with the One Health concept. Despite a strong call for the implementation of such integrated surveillance systems, we still lack a comprehensive overview of existing organizational models for integrated surveillance of ABR. To address this gap, we conducted a scoping review to characterize existing integrated surveillance systems for ABR.
This study suggests that operationalization of integrated surveillance for ABR is still not well established at a global scale, especially in low and middle-income countries and that the surveillance scope is not broad enough to obtain a comprehensive understanding of the complex dynamics of ABR to appropriately inform mitigation measures. Further studies are needed to better characterize the various integration models for surveillance with regard to their implementation context and evaluate the outcome of these models.
Read the paper here.
Lead author: Léo Delpy – Corresponding author: Marion Bordier
Presentations
Mind the gap: a deep dive into official papers of Hungarian antibiotic policy
Poster presentation at 4th International Conference Antimicrobial Resistance – current state and perspectives, 2025
Presenter: Andrea Szabó
Barriers and possibilities: One Health concept in the Hungarian antimicrobial stewardship
Oral presentation at 2nd Debrecen Online Conference on Infectious Diseases in a One Health context (DOCIDOH), 2025
Presenter: Andrea Szabó
Appearance of the One Health approach in the Hungarian antimicrobial stewardship – results of a document analysis
Oral presentation at JOINT EUFEPS – ÖPhG MEETING, 2025
Presenter: Andrea Szabó
DESIGN project: Designing One Health governance for AMR
Oral presentation at JPIAMR Conference, 2025
Presenter: Foekje Stelma
Analysis of the determinants contributing to antibiotic resistance in Senegal using systems analysis from a One Health perspective
Oral presentation at AFROHUN Conference, 2024
Presenter: Mouhamadou Moustapha Sow
Analysis of One Health governance of antimicrobial resistance in Senegal: obstacles and levers for improvement
Poster presentation at World One Health Congress, 2024
Presenter: Mouhamadou Moustapha Sow
Policy network and advocacy coalition framework: A case study of national policy to combat antimicrobial resistance with One Health in Senegal
Poster presentation at World Congress of Epidemiology, 2024
Presenter: Mouhamadou Moustapha Sow
How does the food system influence antimicrobial resistance? A complex systems analysis in five countries
Poster presentation at Geneva Health Forum, 2024
The food system is a key contributor to the emergence and spread of antimicrobial resistance (AMR), with negative repercussions for human, animal and environmental health. While numerous pathways linking the food system to AMR have been identified, the relationships between these factors are complex. Recent research situates AMR as an emerging property of a complex system, but efforts to characterise this system across different countries are limited. Given the multi-sectoral nature of AMR, a One Health perspective has been advocated to understand and control the emergence and transmission of resistance. We use a participatory approach to identify key food system factors that influence AMR, as well as the interconnections and dynamic relationships between them. We undertake this analysis in five countries (Canada, Hungary, the Netherlands, the Philippines and Senegal), spanning high-, middle- and low-income contexts, as well as different governance systems and policy environments.
Presenter: Chloe Clifford Astbury
Applying a One Health approach to the governance of AMR: A JPIAMR-funded project (DESIGN)
Canadian Institutes of Health Research One Health AMR Symposium, 2023
Presenter: Mary Wiktorowicz
Designing One Health Governance for Antimicrobial Stewardship
JPIAMR start-up workshop for HARISSA projects, 2022
Presenter: Mary Wiktorowicz
Media coverage
Governance of antimicrobial stewardship based on the One Health approach on the agenda of a workshop in Senegal
VivAfrik, 2022
Read more here (article in French).
Governance of antimicrobial stewardship based on the One Health approach in Senegal: ISRA and its partners launch the project in Dakar
ISRA, 2022
Read more here (article in French).